Tony Oursler's Synesthesia project features interviews with twelve legendary figures in the downtown music, performance and art scenes: John Cale, Thurston Moore, Dan Graham, Genesis P-Orridge, Kim Gordon, Glenn Branca, Laurie Anderson, Tony Conrad, David Byrne, Lydia Lunch, Alan Vega, and Arto Lindsay. These works were originally included as one element of Oursler and Mike Kelley's multimedia installation The Poetics Project. These conversations reveal fascinating insights and anecdotes from some of the most influential figures in the experimental rock and art underground of the 1970s and '80s, from pre-punk innovators to post-punk icons, from industrial and avant-garde music to noise bands and No Wave.

Genesis P-Orridge, performance artist and vocalist for the iconoclastic English industrial band Throbbing Gristle in the late 1970s, pioneered industrial music. P-Orridge, who went on to form the experimental band Psychic TV, continues to work in music, art, and performance in New York, and is undertaking a long-term "Pandrogeny" project involving a radical identity transformation.