Combining perhaps the only footage from the first Women’s International Day march in San Francisco and rare footage of the second National Lesbian Conference at UCLA, Sisters! is a joyous and vital landmark in feminist, queer, and lesbian filmmaking. Its end credit, scratched into the emulsion of the film, attributes Sisters! to "Agressa," the pseudonym under which Barbara Hammer made some of her earliest films.

"It’s about women taking over the world: women driving trucks, changing Volkswagen engines, and leading the police in new revolutions! It also has footage of women topless, dancing, sweating – with babies on their shoulders! – to the music of the Family of Woman band at the second National Lesbian Conference that took place at UCLA, where Audre Lorde and Kate Millett spoke." — Barbara Hammer